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KMID : 1145120180160030449
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Asian Journal of Beauty and Cosmetology
2018 Volume.16 No. 3 p.449 ~ p.463
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Trends in the Efficacy and Safety of Ingredients in Acne Skin Treatments
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Lee Ju-Yeon
Son Hyo-Jeong
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Abstract
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The aim of this study is to explore trends in safety and efficacy of ingredients used in treatments for acne at a time when the distrust of chemicals is growing. ‘Acne’ is a chronic inflammatory follicular disorder of the skin. Propionibacterium acnes (P. acnes ) plays critical roles in the outbreak of acne by inducing inflammation and forming comedones. Currently, the main methods of treatment for acne vulgaris include oral antibiotics, anti-inflammatory drugs, retinoids, and topical medication. However, prolonged use of these drugs can cause side effects such as skin irritation, dryness, flushing, itching, and resistance to the drug. Thus, there is a demand for effective natural alternatives. Natural extracts that reduce bacterial activity to treat acne are expected to have significantly fewer side effects than existing medications. According to studies anti-bacterial effects are such as Nelumbo nucifera G., Corni fructus , Persicaria perfoliata , Taraxacum mongolicum H., Phragmitis rhizoma , Agrimonia pilosa , Lavandula offcinalis , Cymbopogon martini , Menthapiperita , Eucalyptus globulus , Camellia japonica , ceramide, propolis, epidermal growth factor (EGF) and so on. Further tests of the safety and efficacy of natural extracts with antibacterial properties compared to existing acne medications are needed.
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KEYWORD
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Propionibacterium acnes, Natural plant extracts, Anti-bacterial, EGF, Skin barrier
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